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MT01

Metformin Support

4.8

Daily targeted nutrient support, formulated for people taking biguanides.

$49.99

30-day supply delivered monthly

Expected May 1, 2026

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Clinicians Choice

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Medications Supported:

Metformin
Janumet
Synjardy
Xigduo
Invokamet
Jentadueto
Kombiglyze
Metaglip
Glucovance
Actoplus Met
Kazano
Fortamet
Glumetza
Segluromet
Tijardy XR
Actoplus Met XR
Sitagliptin + Metformin
Empagliflozin + Metformin
Dapagliflozin + Metformin
Glipizide + Metformin
Linagliptin + Metformin
Canagliflozin + Metformin
Empagliflozin + Linagliptin + Metformin
Glyburide + Metformin
Ertugliflozin + Metformin
Pioglitazone + Metformin
Alogliptin + Metformin
Supports:
+26

Clinically-Based Ingredients:

Vitamin B12
Vitamin B12
1,000 mcg
(as methylcobalamin)

Clinical research shows long-term metformin impairs B12 absorption through calcium-dependent pathways. Methylated B12 is the most bioavailable form ensuring proper uptake.

Folate
Folate
340 mcg DFE
(as Quatrefolic® 5-MTHF)

Folate absorption may be reduced during metformin therapy, a concern given its role in antioxidant defense and homocysteine regulation. Quatrefolic® is chosen for its clinically proven bioavailability.

Thiamine (Vitamin B1)
Thiamine (Vitamin B1)
25mg
(as thiamine hydrochloride)

B1 levels can decrease during metformin therapy. Inadequate thiamine levels can compromise neurological function. Thiamine hydrochloride is selected for reliable daily replenishment.

Magnesium Glycinate
Magnesium Glycinate
50mg
(as TRAACS® magnesium bisglycinate chelate)

Magnesium supports glucose metabolism and insulin signaling and is often compromised during metformin use. TRAACS® Glycinate is selected for its clinically validated chelation and gastrointestinal tolerability.

Coenzyme Q10
Coenzyme Q10
50mg
(as ubiquinone)

CoQ10 levels have been shown to decline during metformin therapy, a concern given its role in mitochondrial energy production, antioxidant defense, and cellular protection in kidney tissue.

Antidote Complex

AntidoteComplex™ is our proprietary technology developed to optimize absorption & bioavailability

Pill

How to Use:

Take 1 capsule daily with food, in the AM or PM.

Clean Formula Standards:

Gluten-FreeVeganGMO FreeClinically Tested

30-Day Guarantee

Request a refund within 30 days of your order delivery for your money back.

Free Shipping

US orders ship within 1-2 business days. Limited international shipping.

Flexible Plans

Reschedule your deliveries or cancel your subscription any time.

Commonly Taken Alongside:
Statin Support
Statin Support
Statin Support
Once Daily Capsule
Lisinopril Support
Lisinopril Support
Lisinopril Support
Once Daily Capsule
Losartan Support
Losartan Support
Losartan Support
Once Daily Capsule
Amlodipine Support
Amlodipine Support
Amlodipine Support
Once Daily Capsule
Aspirin Support
Aspirin Support
Aspirin Support
Once Daily Capsule
Omeprazole Support
Omeprazole Support
Omeprazole Support
Once Daily Capsule

Questions, answered.

Yes. Antidote formulas were developed to be used together, with ingredient selection and nutrient overlap carefully considered across all products. Most people choose to take more than one formula as part of their routine. As always, we recommend reviewing your supplement use with your healthcare provider.

Everyone’s body responds differently. Some people may notice changes within a few weeks, while others may require more consistent use over time. Because Antidote formulas support nutrient repletion rather than immediate effects, results are often gradual. We recommend consistent daily use for sustained support.

While most people notice symptoms associated with low nutrients, it can vary and isn't always intuitive. Blood testing is the most accurate way to evaluate nutrient levels. A healthcare provider can help interpret labs and determine whether supplementation makes sense.

Got More Questions?

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4.8 Stars
Start Feeling Better
on Your Medication

Exactly what I was missing!

I’ve been using Antidote for a few weeks now and already feel less fatigued and achey. I love that it’s just one pill per day!

Sarah P.Early Access

Easy addition to my routine.

Had no idea my medication was depleting so many things, but I’m excited to to have this product in my daily routine.

David M.Early Access

Thoughtfully Designed!

I was having daily cramps before I started taking these nutrients! I am excited to try a second formula too since they work well together.

Ashley S.Early Access